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| 2022-08-18 17:15:44 | San Francisco Golden Gators | | Demoted | Marlon Riley | Little Rock Fighting Farmers |
| 2022-08-18 17:15:36 | San Francisco Golden Gators | | Demoted | Hunter Thomas | Little Rock Fighting Farmers |
| 2022-08-18 17:15:30 | San Francisco Golden Gators | | Demoted | David Skinner | Little Rock Fighting Farmers |
| 2022-08-18 17:15:24 | San Francisco Golden Gators | | Demoted | Harry Haley | Little Rock Fighting Farmers |
| 2022-08-18 17:09:50 | Las Vegas Dark Knights | | Drop | Neil Oehler | |
| 2022-08-18 17:05:12 | Las Vegas Dark Knights | | Drop | Jonathan Cole | |
| 2022-08-18 16:49:32 | Santiago Sharks | | Promoted | Julio Tung | San Diego Sabercats |
| 2022-08-18 16:48:04 | San Diego Sabercats | | Demoted | Elmer Robinson | Santiago Sharks |
| 2022-08-18 16:44:48 | San Diego Sabercats | | Demoted | Justin Cox | Santiago Sharks |
| 2022-08-18 16:44:02 | Santiago Sharks | | Promoted | Sonny Kincaid | San Diego Sabercats |
| 2022-08-18 16:37:52 | Santiago Sharks | | Promoted | Elmer Robinson | San Diego Sabercats |
| 2022-08-18 11:12:34 | Toronto Huskies | | Promoted | Gino Bulloch | Salt Lake City Night Hawks |
| 2022-08-16 14:25:28 | South Dakota Blackhawks | | Promoted | Isaac Reddington | Philadelphia Assassins |
| 2022-08-16 14:24:56 | South Dakota Blackhawks | | Promoted | Valentine Lovett | Philadelphia Assassins |
| 2022-08-14 17:53:20 | Philadelphia Assassins | | Demoted | Valentine Lovett | South Dakota Blackhawks |
| 2022-08-14 12:05:02 | Portland Hipsters | | Demoted | Hunter King | Montreal Ice Cats |
| 2022-08-14 12:04:44 | Montreal Ice Cats | | Promoted | Christian Sawyer | Portland Hipsters |
| 2022-08-13 15:26:26 | Minneapolis Bricklayers | | Demoted | Connor Asbell | Santo Domingo Lazy Dogs |
| 2022-08-13 15:25:52 | Santo Domingo Lazy Dogs | | Promoted | Dshawn Markovitz | Minneapolis Bricklayers |
| 2022-08-12 14:10:46 | Birmingham Venom | | Promoted | Harold Lewis | Boston Bannerman |
| 2022-08-11 14:10:00 | South Dakota Blackhawks | | Promoted | Chad Hammond | Philadelphia Assassins |
| 2022-08-11 14:09:42 | Philadelphia Assassins | | Demoted | Danny Callahan | South Dakota Blackhawks |
| 2022-08-11 14:08:14 | Philadelphia Assassins | Henry Knox | Add/Drop | | |
| 2022-08-11 14:07:08 | Philadelphia Assassins | | Demoted | Chad Hammond | South Dakota Blackhawks |
| 2022-08-11 11:55:40 | Sao Paulo Jackalopes | | Promoted | Noah Sims | Cincinnati Skyliners |