|
| 2022-04-23 15:02:40 | Indianapolis Tornadoes | | Demoted | Emmanuel Ray | Buenos Aires Eagles |
| 2022-04-23 15:01:44 | Portland Hipsters | | Demoted | Joshua Bailey | Montreal Ice Cats |
| 2022-04-23 15:01:30 | Portland Hipsters | | Demoted | Alex Kirksey | Montreal Ice Cats |
| 2022-04-23 15:01:18 | Portland Hipsters | | Demoted | Shawn Kirkland | Montreal Ice Cats |
| 2022-04-23 15:00:58 | Montreal Ice Cats | | Promoted | Hunter Gardner | Portland Hipsters |
| 2022-04-23 15:00:00 | Philadelphia Assassins | 1st round pick in season 33 | Acquired via trade | 1st round pick in season 33 | Memphis Express |
| 2022-04-23 15:00:00 | Philadelphia Assassins | 1st round pick in season 34 | Acquired via trade | | Memphis Express |
| 2022-04-23 15:00:00 | Philadelphia Assassins | 1st round pick in season 33 | Acquired via trade | 1st round pick in season 33 | Indianapolis Tornadoes |
| 2022-04-23 15:00:00 | Philadelphia Assassins | 2nd round pick in season 33 | Acquired via trade | | Indianapolis Tornadoes |
| 2022-04-23 14:53:06 | Salt Lake City Night Hawks | | Demoted | Noah Riley | Toronto Huskies |
| 2022-04-23 14:53:00 | Salt Lake City Night Hawks | | Demoted | Gage Cunningham | Toronto Huskies |
| 2022-04-23 14:52:52 | Salt Lake City Night Hawks | | Demoted | Devan McLean | Toronto Huskies |
| 2022-04-23 14:52:42 | Salt Lake City Night Hawks | | Demoted | Dustin Mezo | Toronto Huskies |
| 2022-04-23 14:47:48 | Indianapolis Tornadoes | | Demoted | Alexander Derrick | Buenos Aires Eagles |
| 2022-04-23 14:30:48 | Indianapolis Tornadoes | | Demoted | Andrew Sigle | Buenos Aires Eagles |
| 2022-04-23 14:25:44 | Cincinnati Skyliners | | Demoted | Jamarius Peters | Sao Paulo Jackalopes |
| 2022-04-23 14:25:20 | Orlando Bombers | | Demoted | Trevor Lucas | Ottawa Mt. Hawks |
| 2022-04-23 14:25:08 | Orlando Bombers | | Demoted | Alejandro Kessler | Ottawa Mt. Hawks |
| 2022-04-23 14:24:52 | Orlando Bombers | | Demoted | Jorge Stankiewicz | Ottawa Mt. Hawks |
| 2022-04-23 13:58:56 | Miami Macho Men | | Demoted | Justin Dennis | Nashville Night Owls |
| 2022-04-23 13:40:12 | New Orleans Hurricanes | | Demoted | James Wiley | Detroit Gear Daddies |
| 2022-04-23 13:39:34 | New Orleans Hurricanes | | Demoted | Jacob Cawthorne | Detroit Gear Daddies |
| 2022-04-23 12:58:00 | Las Vegas Dark Knights | 2nd round pick in season 33 | Acquired via trade | 1st round pick in season 33 | Philadelphia Assassins |
| 2022-04-23 12:58:00 | Las Vegas Dark Knights | Samuel Meeks | Acquired via trade | | Philadelphia Assassins |
| 2022-04-23 12:58:00 | Las Vegas Dark Knights | 1st round pick in season 34 | Acquired via trade | | Philadelphia Assassins |